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C1QA Polyclonal Antibody, 20ul Lentiviral Packaging The encoded mechanosensing protein contains

SKU: 96278759901

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C1QA Polyclonal Antibody, 20ul Lentiviral Packaging The encoded mechanosensing protein containsThis gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A chains, six B chains, and six C chains. Each chain contains a collagen like region located near the N terminus and a C terminal globular

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Description

The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension| resulting in the reconfiguration of cadherin-actin filament connections

Additional transcript variants have been described but their biological validity has not been confirmed

Moderate expression in heart and liver| low expression in skeletal muscle| kidney and testis

and cytoskeletal rearrangement

C1QA Polyclonal Antibody, 20ul Lentiviral Packaging The encoded mechanosensing protein containsThis gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A chains, six B chains, and six C chains. Each chain contains a collagen like region located near the N terminus and a C terminal globular

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