Human Nlr Family, Card Domain Containing 3, NLRC3 ELISA Kit, 96T Adenovirus Packaging The function of RIOK1 has

The function of RIOK1 has not been determined

GO annotations related to this gene include metallocarboxypeptidase activity

May regulate the intracellular trafficking of ADR1B

(Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry (PubMed: 12356718

Human Nlr Family, Card Domain Containing 3, NLRC3 ELISA Kit, 96T Adenovirus Packaging The function of RIOK1 hasNegative regulator of the innate immune response (PubMed: 15705585, PubMed: 22863753, PubMed: 25277106). Attenuates signaling pathways activated by Toll like receptors (TLRs) and the DNA sensor STING TMEM173 in response to pathogen associated molecular patterns, such as intracellular poly(dA: dT), but not poly(I: C), or in response to DNA virus infection, including that of Herpes simplex virus 1 (HSV1) (By similarity) (PubMed: 22863753). May affect