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p57 Polyclonal Antibody, 20ul[BT-AP06843] Plasma and oncogenic processes
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p57 Polyclonal Antibody, 20ul[BT-AP06843] Plasma and oncogenic processesCDKN1C is imprinted, with preferential expression of the maternal allele. The cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been
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