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PDE4B Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance alpha 4 contains the C-terminal

SKU: 95909634847

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PDE4B Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance alpha 4 contains the C-terminalThis gene is a member of the type IV cyclic AMP (cAMP) specific cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding

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Description

alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains

This gene is thought to be involved in CNS development

This protein contains 6 WD repeats and is highly expressed in the heart

Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia

PDE4B Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance alpha 4 contains the C-terminalThis gene is a member of the type IV cyclic AMP (cAMP) specific cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding

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