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Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 50ul Antibody Development These genes are regulated by

Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 50ul Antibody Development These genes are regulated by

Name: Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 50ul Antibody Development These genes are regulated by
Brand: www.drbramiyohan.com
SKU: 95875345869
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SKU: 95875345869

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Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 50ul Antibody Development These genes are regulated byThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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Description

These genes are regulated by different mechanisms

targeting specific proteins for ubiquitin-mediated proteolysis

the mature protein downregulates fibrinolysis

The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins

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