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TLK2 Polyclonal Antibody, 50ul Cell Dissociation The encoded preproprotein is proteolytically

SKU: 95690459479

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TLK2 Polyclonal Antibody, 50ul Cell Dissociation The encoded preproprotein is proteolyticallyTLK2 encodes a nuclear serine threonine kinase that was first identified in Arabidopsis. The serine threonine protein kinase tousled like 2 is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3 H4 chaperone. This protein is associated with double strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17.

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Description

The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit

and a corresponding pseudogene has been found on chromosome 22

Alternatively spliced transcript variants encoding different isoforms exist

It consists of two concentric membranes perforated by nuclear pores

TLK2 Polyclonal Antibody, 50ul Cell Dissociation The encoded preproprotein is proteolyticallyTLK2 encodes a nuclear serine threonine kinase that was first identified in Arabidopsis. The serine threonine protein kinase tousled like 2 is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3 H4 chaperone. This protein is associated with double strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17.

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