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Ref-1 Polyclonal Antibody, 100ul[BT-AP07735] Protein Post-translational Modification Among its related pathways are

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Ref-1 Polyclonal Antibody, 100ul[BT-AP07735] Protein Post-translational Modification Among its related pathways areApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

Among its related pathways are Golgi-to-ER retrograde transport and Factors involved in megakaryocyte development and platelet production

Interacts with SERPING1

TnI-skeletal-slow-twitch

coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al

Ref-1 Polyclonal Antibody, 100ul[BT-AP07735] Protein Post-translational Modification Among its related pathways areApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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