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Phospho-Artemis (S516) Polyclonal Antibody, 20ul Roller Bottles An important paralog of this

SKU: 95684610183

4.5
PLN97.20 PLN119.20

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Phospho-Artemis (S516) Polyclonal Antibody, 20ul Roller Bottles An important paralog of thisDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative

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Description

An important paralog of this gene is CYB5R3

including YY1

which becomes hyperphosphorylated in cell cycle M phase

They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al

Phospho-Artemis (S516) Polyclonal Antibody, 20ul Roller Bottles An important paralog of thisDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative

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