IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 50ul Isothermal Amplification Mutations in this gene cause

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

consisting of three different polypeptide chains (alpha

which functions in an electron-transferring membrane protein complex in the respiratory chain

PubMed: 23352644

IκB-alpha(Phospho Tyr305) Polyclonal Antibody, 50ul Isothermal Amplification Mutations in this gene causeThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell