p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library Two transcript variants encoding different

Two transcript variants encoding different proteins have been found for this gene

GO annotations related to this gene include actin binding and WW domain binding

which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane

This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains

p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library Two transcript variants encoding differentTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.