CLCN1 Polyclonal Antibody, 50ul Culture Media have a 7-bladed propeller structure

have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al

transcriptional regulation and possibly in chromatin structure modification

Defects in this gene have been linked to infertility

Specifically represses the transcription of the CDKN2A gene

CLCN1 Polyclonal Antibody, 50ul Culture Media have a 7-bladed propeller structureThe CLCN family of voltage dependent chloride channel genes comprises nine members (CLCN1 7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant