Rat Insulin-like Growth Factors 1 Receptor, IGF-1R ELISA Kit, 96T DNA Fragments It is also involved in

It is also involved in oogenesis and in neuronal differentiation

Mutations in this gene are associated with several congenital cardiovascular malformations

Channels containing GRIN1 and GRIN2A have lower sensitivity to glutamate and faster deactivation kinetics than Channels formed by GRIN1 and GRIN2B (PubMed: 28384476)

Multifunctional protein with various roles in different cellular compartments

Rat Insulin-like Growth Factors 1 Receptor, IGF-1R ELISA Kit, 96T DNA Fragments It is also involved inReceptor tyrosine kinase which mediates actions of Insulin like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates,