eIF2 alpha(Phospho Ser51) Polyclonal Antibody, 50ul Custom RNA Oligos This gene is located in

This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2

Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy

The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner| and is selectively localized at the basolateral membrane in polarized epithelial cells

Hepatocyte growth factor-regulated tyrosine kinase substrate encoded by HGS regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors

eIF2 alpha(Phospho Ser51) Polyclonal Antibody, 50ul Custom RNA Oligos This gene is located inThe translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36 kD EIF2 alpha subunit (EIF2S1), the 38 kD EIF2 beta subunit (EIF2S2; MIM 603908), and the 52 kD EIF2 gamma subunit (EIF2S3; MIM 300161). The rate of