PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07262] Stepper which overlaps with this gene

which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region

Originally localized to both chromosomes 2 and 7

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes

sebaceous glands

PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07262] Stepper which overlaps with this geneThe protein encoded by PLCG1 (phospholipase C gamma 1) catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate