Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09132] High Speed Micro-Centrifuges subcellular location:In unstimulated cells

subcellular location:In unstimulated cells

This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate| suggesting a role in repair of free-radical mediated DNA double-strand breaks

This nuclear coactivator is proteolytically cleaved at one of the six possible sites

Knockout studies in mice suggested the role of this

Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09132] High Speed Micro-Centrifuges subcellular location:In unstimulated cellsTOP2A (topoisomerase (DNA) II alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass