NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody, 20ul[BT-AP05825] Mini dry bath RAN (ras-related nuclear protein) is

RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family| with an N-terminal PDZ domain| a central src homology 3 region (SH3)| and a C-terminal guanylate kinase-like (GUK) domain

Two transcript variants encoding different isoforms have been found for NME1

The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody, 20ul[BT-AP05825] Mini dry bath RAN (ras-related nuclear protein) isThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and