BID (p11| Cleaved-Ser100) Rabbit Polyclonal Antibody, 50ul Plasmid Preparation This gene lies in close

This gene lies in close proximity to thymidylate synthase gene on chromosome 18

The protein functions to initiate or augment the early phase of T-cell activation

It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth

Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells

BID (p11| Cleaved-Ser100) Rabbit Polyclonal Antibody, 50ul Plasmid Preparation This gene lies in closeIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by