CRTAP Rabbit Polyclonal Antibody, 100ul ADME In rat| this protein localizes

In rat| this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal

Some haplotypes of this gene show a positive association with schizophrenia

The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly

their biological validity has not been determined

CRTAP Rabbit Polyclonal Antibody, 100ul ADME In rat| this protein localizesThe protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta a connective tissue disorder characterized by bone fragility and low bone mass.