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p70 S6 Kinase alpha Polyclonal Antibody, 20ul[BT-AP12705] Plates & Dishes Dysregulation of this gene has

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p70 S6 Kinase alpha Polyclonal Antibody, 20ul[BT-AP12705] Plates & Dishes Dysregulation of this gene hasThis gene encodes a member of the ribosomal S6 kinase family of serine threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N

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Description

Dysregulation of this gene has been associated with the growth and progression of certain cancers

and binds specifically to MAP kinase kinase MAP2K1/MEK1

Studies suggest this is a cancer suppressor gene

BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner

p70 S6 Kinase alpha Polyclonal Antibody, 20ul[BT-AP12705] Plates & Dishes Dysregulation of this gene hasThis gene encodes a member of the ribosomal S6 kinase family of serine threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N

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