NCoA-3 Monoclonal Antibody, 100ul Thermo Mix Expression of the mouse homolog

Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling

The encoded protein may play a role in apoptosis in a caspase-dependent manner

contain a tetratricopeptide repeat (TPR) domain

this gene is not induced by serum or glucocorticoids

NCoA-3 Monoclonal Antibody, 100ul Thermo Mix Expression of the mouse homologThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several