Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction Members of this protein family

Members of this protein family have an affinity for beta-galactosides

MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al

and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences

More than a dozen pseudogenes of this gene have been identified

Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction Members of this protein familyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.