TIG1 Polyclonal Antibody, 100ul Immunoassays DNA repair protein complementing XP-G

DNA repair protein complementing XP-G cells may also function in other cellular processes

but mutations in this gene have not been associated with the disease

This gene is expressed mainly in testis with weak expression in the brain

This gene exhibits tissue-specific imprinting

TIG1 Polyclonal Antibody, 100ul Immunoassays DNA repair protein complementing XP-GThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.