HNF1A Polyclonal Antibody, 100ul Funnels CCT8 encodes the theta subunit

CCT8 encodes the theta subunit of the CCT chaperonin

mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs

The protein localizes to the cytoplasm

and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR)

HNF1A Polyclonal Antibody, 100ul Funnels CCT8 encodes the theta subunitThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different