Podocan Polyclonal Antibody, 100ul NGS Oligos Increased expression of this protein

Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines

Acts by interacting with the second WW domain of ITCH

Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene

The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters

Podocan Polyclonal Antibody, 100ul NGS Oligos Increased expression of this proteinThe podocan encoded by PODN is a member of the small leucine rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine rich cluster followed by a leucine rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury.