GASP-1 Polyclonal Antibody, 100ul 3D Culture Evidence indicates that mutations in

Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)

This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene

including roles in the differentiation and arrangement of tissue thre

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain

GASP-1 Polyclonal Antibody, 100ul 3D Culture Evidence indicates that mutations inGPRASP1 (G protein coupled receptor associated sorting protein 1) encodes a member of the GPRASP (G protein coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down regulation of a variety of G protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta