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KCNK4 (TRAAK) Polyclonal Antibody, 100ul Custom DNA Oligos also called infantile malignant osteopetrosis

SKU: 92250766716

4.1
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KCNK4 (TRAAK) Polyclonal Antibody, 100ul Custom DNA Oligos also called infantile malignant osteopetrosisThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia

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Description

also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2)

They form a three-tiered signaling module composed of MAPKKKs| MAPKKs| and MAPKs

in which it interacts directly with SKP1

Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons

KCNK4 (TRAAK) Polyclonal Antibody, 100ul Custom DNA Oligos also called infantile malignant osteopetrosisThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia

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