Tie-1 Polyclonal Antibody, 50ul Centrifuges This receptor has been shown

This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis

The encoded protein is expressed in endothelial cells

Alternatively spliced transcript variants have been described for PDE10A

CD47 has been demonstrated to be a ligand for this receptor protein

Tie-1 Polyclonal Antibody, 50ul Centrifuges This receptor has been shownTIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth