Z280B Polyclonal Antibody, 50ul Sample Library Tubes This gene exists on chromosome

This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor

The HMG-box containing 3 contains an HMG-box domain found in DNA binding proteins such as transcription factors and chromosomal proteins

such as Inhibitor-2 (Inh2)

Extensive alternative splicing has been described

Z280B Polyclonal Antibody, 50ul Sample Library Tubes This gene exists on chromosomeThe protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein coding.