ORC1 Polyclonal Antibody, 100ul Syringe Filter Its physiological role is thought

Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle

enzyme regulation:Inhibited by cGMP

the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients

Mouse studies suggested an essential role of this protein in spermatogenesis

ORC1 Polyclonal Antibody, 100ul Syringe Filter Its physiological role is thoughtORC1 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. Origin recognition complex subunit 1 contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.