SPDEF Polyclonal Antibody, 100ul Recombinant Ab Production Multiple alternately spliced transcript variants

Multiple alternately spliced transcript variants which encode different protein isoforms have been described

The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits

The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide| and is found in either a latent form composed of a mature peptide homodimer| a LAP homodimer| and a latent TGF-beta binding protein| or in an active form consisting solely of the mature peptide homodimer

SPDEF Polyclonal Antibody, 100ul Recombinant Ab Production Multiple alternately spliced transcript variantsThe protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen independent transactivator of prostate specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor association than other cancer associated