NFKappaB-p65 Polyclonal Antibody, 100ul[BT-AP05993] Peptide Synthesis |subcellular location:Isoform 4 is found

|subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm

This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis

and single nucleotide polymorphisms in this gene are associated with blood pressure variation

Alternatively spliced transcript variants encoding the same protein have been found for CLDN5

NFKappaB-p65 Polyclonal Antibody, 100ul[BT-AP05993] Peptide Synthesis |subcellular location:Isoform 4 is foundNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of RELA, RELA. Four