Desmin Polyclonal Antibody, 50ul[BT-AP02569] Enzymes The use of alternative splice

The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family

the interaction is direct and specific for CENPA since it does not interact with H3

It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set

Desmin Polyclonal Antibody, 50ul[BT-AP02569] Enzymes The use of alternative spliceDES encodes a muscle specific class III intermediate filament. Homopolymers of desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in DES are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.