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GDF11 Rabbit Polyclonal Antibody, 50ul Cell fragmentation and collection GIMAP5 encodes GTPase IMAP family

SKU: 90456401725

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GDF11 Rabbit Polyclonal Antibody, 50ul Cell fragmentation and collection GIMAP5 encodes GTPase IMAP familyThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein plays a role in the development of the nervous and

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Description

GIMAP5 encodes GTPase IMAP family member 5 belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins

SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro)

The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB)| both anchored in the membrane

disease:Defects in GRN are the cause of ubiquitin-positive frontotemporal dementia (UP-FTD)

GDF11 Rabbit Polyclonal Antibody, 50ul Cell fragmentation and collection GIMAP5 encodes GTPase IMAP familyThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein plays a role in the development of the nervous and

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