SALL1 Polyclonal Antibody, 50ul Vortex Mixer Alternative splicing of downstream exons

Alternative splicing of downstream exons is also observed| which results in different forms of the stimulatory G-protein alpha subunit| a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins

Reciprocal translocations between chromosomes 22 and 17

cytoskeletal rearrangements and the JNK/SAPK signaling cascade

SALL1 Polyclonal Antibody, 50ul Vortex Mixer Alternative splicing of downstream exonsThe protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes Brocks syndrome (TBS) as well as bronchio oto renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.