PAPP1 Polyclonal Antibody, 20ul Culture Plate Inserts Protein GPR107 involved in Golgi-to-ER

Protein GPR107 involved in Golgi-to-ER retrograde transport

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma

Its overall structure is most related to the former

A pseudogene has been identified on chromosome 22

PAPP1 Polyclonal Antibody, 20ul Culture Plate Inserts Protein GPR107 involved in Golgi-to-ERThis gene encodes a secreted metalloproteinase which cleaves insulin like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.