Sgo2 Polyclonal Antibody, 100ul Pipette Filler TSEN54 encodes a subunit of

TSEN54 encodes a subunit of the tRNA splicing endonuclease complex

The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses

Members of this family contain a single transmembrane domain

It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells

Sgo2 Polyclonal Antibody, 100ul Pipette Filler TSEN54 encodes a subunit ofCooperates with PPP2CA to protect centromeric cohesin from separase mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II anaphase II transition, preventing premature release of meiosis specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate