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GNAS2 Rabbit Polyclonal Antibody, 50ul Plasmid Preparation Multiple alternatively spliced transcript variants

SKU: 89262442565

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GNAS2 Rabbit Polyclonal Antibody, 50ul Plasmid Preparation Multiple alternatively spliced transcript variantsThis locus has a highly complex imprinted expression pattern. It gives rise to maternally paternally and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the

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Description

Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed

This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L)| and transduces an apoptosis signal

In addition| one of the transcripts contains a second overlapping ORF| which encodes a structurally unrelated protein - Alex

ZFP36L2 is a member of the TIS11 family of early response genes

GNAS2 Rabbit Polyclonal Antibody, 50ul Plasmid Preparation Multiple alternatively spliced transcript variantsThis locus has a highly complex imprinted expression pattern. It gives rise to maternally paternally and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the

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