PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling This cyclin binds both CDK2

This cyclin binds both CDK2 and CDC2 kinases

It seems to interact in a multiprotein complex with RbAp48 and HDAC3

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

100% integrity test Sterilized and non-sterilized available

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling This cyclin binds both CDK2disease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: