E2F-6 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos It also plays a role

It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2| which associates with MBP

The encoded protein may be involved in endocytic sorting

It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity

a glycine/phenylalanine-rich region

E2F-6 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos It also plays a roleE2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene