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EP-CAM Polyclonal Antibody, 20ul[BT-AP02987] Gel & Buffers Calreticulin can inhibit the binding

SKU: 87495643746

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SEK97.20 SEK118.20

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EP-CAM Polyclonal Antibody, 20ul[BT-AP02987] Gel & Buffers Calreticulin can inhibit the bindingEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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Description

Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo

the encoded protein is sequestered in the cytoplasm

BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns

The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription

EP-CAM Polyclonal Antibody, 20ul[BT-AP02987] Gel & Buffers Calreticulin can inhibit the bindingEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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