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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The protein can also interact

SKU: 87221824854

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SEK162.00 SEK202.00

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The protein can also interactThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

The protein can also interact with several HIV proteins

and manic depression

The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases

and in primary human tumors and cancer cell lines

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The protein can also interactThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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