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EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein (sphingosine-1-phosphate receptor

SKU: 87148221178

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EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein (sphingosine-1-phosphate receptorThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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Description

The encoded protein (sphingosine-1-phosphate receptor 2) is a receptor for sphingosine 1-phosphate

Decreased expression of this gene is associated with splenic marginal zone lymphomas

The encoded protein may be involved in endosome-to-Golgi transport

Alternative splicing results in multiple trans

EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein (sphingosine-1-phosphate receptorThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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