PRAK Polyclonal Antibody, 100ul[BT-AP07382] 3D Culture Some transcripts contain a differentially

Some transcripts contain a differentially methylated region (DMR) at their 5' exons| and this DMR is commonly found in imprinted genes and correlates with transcript expression

Mutations in this gene are associated with osteoarthritis in humans

The protein localizes to plasma membrane ruffles

The protein encoded by PLN (phospholamban) is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

PRAK Polyclonal Antibody, 100ul[BT-AP07382] 3D Culture Some transcripts contain a differentiallyThe protein encoded by MAPKAPK5 (mitogen activated protein kinase activated protein kinase 5) is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation