Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging The product of CRK has

The product of CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways

Mutations in this gene cause epidermolytic palmoplantar keratoderma

Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins

HNRP proteins have also been identified outside of the nucleoplasm

Kininogen 1 Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging The product of CRK hasThis gene uses alternative splicing to generate two different proteins high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is