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PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing alpha 4 contains the C-terminal

SKU: 86959713778

4.7
PLN123.75 PLN170.75

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PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing alpha 4 contains the C-terminalCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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Description

alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains

RBM5 is located within the tumor suppressor region 3p21

The WW domains are essential for localization to nuclear speckles

EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen

PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing alpha 4 contains the C-terminalCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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