Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper Shb is a widely expressed

Shb is a widely expressed protein that localizes to both the cell membrane and the cytoplasm and plays an important role in signal transduction

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disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)

subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane

Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper Shb is a widely expressedThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).