p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix In one family with congenital

In one family with congenital myasthenic syndrome affecting limb-girdle muscles| a mutation in this gene was found

GO annotations related to this gene include DNA-directed RNA polymerase activity and RNA polymerase I transcription factor binding

and epsilon subunits

ring-box 1 (Rbx1) and Cullin2 (Cul2)

p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix In one family with congenitalTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni