P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 50ul Gel & Buffers Symptoms associated with mutations in

Symptoms associated with mutations in this gene

Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins

and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity

Multiple transcript variants encoding different isoforms have been found for CALCA

P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 50ul Gel & Buffers Symptoms associated with mutations inThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.