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Akt1 Polyclonal Antibody, 100ul[BT-AP00340] Transporters Previously thought to interact in

SKU: 86403533429

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SEK141.00 SEK186.00

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Akt1 Polyclonal Antibody, 100ul[BT-AP00340] Transporters Previously thought to interact inThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Previously thought to interact in an exclusively homophilic manner

a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex

The product of this reaction is glucosylceramide

Stat5 is constitutively active in some leukemic cell types

Akt1 Polyclonal Antibody, 100ul[BT-AP00340] Transporters Previously thought to interact inThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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