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Human Interleukin-10 Receptor Subunit Alpha, IL10RA ELISA Kit, 96T Filtration The protein encoded by IKBKB

SKU: 86385268510

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Human Interleukin-10 Receptor Subunit Alpha, IL10RA ELISA Kit, 96T Filtration The protein encoded by IKBKBCell surface receptor for the cytokine IL10 that participates in IL10 mediated anti inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, allowing IL10RB to bind IL10 as well (PubMed: 16982608). In turn, the heterotetrameric assembly complex, composed of two subunits of IL10RA and IL10RB, activates the kinases JAK1 and TYK2 that are constitutively

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Description

The protein encoded by IKBKB phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex

This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis

These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents

Binds to RNA

Human Interleukin-10 Receptor Subunit Alpha, IL10RA ELISA Kit, 96T Filtration The protein encoded by IKBKBCell surface receptor for the cytokine IL10 that participates in IL10 mediated anti inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, allowing IL10RB to bind IL10 as well (PubMed: 16982608). In turn, the heterotetrameric assembly complex, composed of two subunits of IL10RA and IL10RB, activates the kinases JAK1 and TYK2 that are constitutively

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